RATTAN JUNEJA, ADAM GOLAS, JONI CARROLL, DEBORAH NELSON, CORBIN ROUDEBUSH, SAMUEL FLANDERS.

Aim: We evaluated the effectiveness of a computerized IV Insulin (IVI) protocol in achieving and maintaining Blood Glucose (BG) targets. Once the physician orders IV insulin with a target BG range, the IVI program recommends an insulin infusion rate and provides alarms for BG checks. With each new BG entered into the program, a new infusion rate is recommended and the cycle repeats. Numerous safety and record keeping features are built into the program.

 

Results: Of the 4754 drip runs since the program was initiated we have analyzed data on 3473 runs that had at least 10 BG tests. Drips that were continuations of previous drips (thus with low starting sugars) were excluded. The majority of drips were run using a target BG range of 80-110 mg/dl (2,980 of 3,473). Blood Glucose target was achieved in 2959/2980 runs (99.3%) with a median starting BG of 191 mg/dl. Of these drips, 496/2980 (16.6%) reached target on the first BG after starting insulin infusion. Of those not reaching target at the first BG, the median time before reaching target was 6 hours, after which 68% BG&apos;s remained in target with average glucose of 97 mg/dl. The overall prevalence of hypoglycemia (BG < 50 mg/dl) was only 0.4%.

 

Conclusions: Our computerized IVI program offers a safe and effective means of rapidly achieving and maintaining glucose targets in hospitalized patients